Pemfigus SYMPTOMS DIAGNOSIS TREATMENT

Pemfigus SYMPTOMS DIAGNOSIS TREATMENT

Pemfigus SYMPTOMS DIAGNOSIS TREATMENT

Pemfigus can be a rare skin condition, characterized by a good blisters-blisters (bula) of varied sizes on the surface of your skin and mucous membranes (membrane mouth, vagina, penis and other mucous membranes).

Pemfigus frequently within middle age or old age.

Rarely attacked the kids.

The reason for

Pemfigus is definitely an autoimmune disorder, when the defense mechanisms produces antibodies that attack specific proteins on top of the epidermis and mucous membranes.

These antibodies result in a reaction which led to the separation of epidermal cells of the epidermis (akantolisis).

A certain root cause of the formation of antibodies contrary to the body's own tissues, is not known.

Certain cases occurred due to a reaction to the drugs (penisilamin, kaptopril).

SYMPTOMS

The primary manifestation of pemfigus is soft fluid blisters of sizes; on some forms, coupled with occurance of pemfigus patches of scaly patches.

An easy pinch or friction could easily bring about terlepasnya your skin surface on the layers beneath it.

Blisters often appear first within the mouth after which it broke up and formed the open wound caused pain.

Then blisters and sores looks prior to the entire miscellaneous membranes the mouth exposed.

The same principle also happened about the skin. Blisters first appeared on normal skin, then broke and left the rough scab sores.

Blisters can spread widely and blisters that burst may have chlamydia.

DIAGNOSIS

The verification will be based upon symptoms and upheld outcomes of physical examinations.

Tzanck test and biopsy results showed a akantolisis process.

TREATMENT

The aim of treatment is to halt occurance of a new Bull.

To accomplish this goal, performed an incomplete suppression on the immune system with corticosteroid drugs per-oral (orally), but as a result the body gets to be more responsive to infection.

Usually at 7-10hari first, given high-dose corticosteroid overdose then descended gradually.

Other medications that will suppress the disease fighting capability are:

-methotrexat

-cyclophosphamide

-azathioprin

Gold salts.

Immunosupresan drugs (suppressor of body's defence mechanism) might be given simultaneously with plasmaferesis (screening of antibodies in the blood).

To conquer the problem, given antibiotics.

In the event the ailment is severe, the affected person needs to be hospitalized.

Fluid, electrolyte and protein is provided using an infusion.

To reduce the pain the result of a wound inside mouth, might be given a suction bubble containing the drug.