Autoimmune Disorders

autoimmune disorders of the skin

 Autoimmune Disorders

Autoimmune disorder is a malfunction of the body's immune system makes the body attacks its own tissues.

Keep the body's immune system against what invisibility as foreign or dangerous substances. Such material including microorganisms, parasites (such as worms), cancer cells, and even organ and tissue transplantation. Materials that can stimulate the immune response is called an antigen. Antigens are molecules that may be present in the cell or on the surface of cells (such as bacteria, viruses, or cancer cells). Some antigens, such as pollen or food molecules, in their own.

Cells even in people who have their own networks can have antigen. But, usually, the immune system reacts only to antigens from foreign or dangerous substances, not to antigens from people who have a network of oneself. However, sometimes the immune system is damaged, the body's own tissues translates as foreign and produces antibodies (called autoantibodies) or immune cells to target and attack the body's own tissues. This response is called an autoimmune reaction. It results in inflammation and tissue damage. Such effects may be an autoimmune disorder, but some people produce such a small amount that autoantibodies autoimmune disorder does not occur. Autoimmune Disorders

Some common autoimmune disorders such as rheumatoid arthritis, systemic lupus erythematosus (lupus), and vasculitis, among others. Additional disease that is associated to such autoimmune glomerulonephritis, Addison's disease, mixed connective tissue disease, Sjogren's syndrome, progressive systemic sclerosis, and some cases of infertility.

CAUSE

Autoimmune reactions can be triggered by several things:

* A substance in the body that is normally restricted in certain areas (and thus hidden from the immune system) darah.Misalnya released into the bloodstream, a blow to the eye can make the fluid in the eyeball blood. Fluid released into the bloodstream to stimulate the immune system eyes recognize as foreign and attack them.

* Normal body substance is changed, eg, by viruses, drugs, sunlight, or radiation. Material compounds that change may seem foreign to the immune system. For example, a virus can infect and thereby alter cell in the body. The virus-infected cells stimulate the immune system to attack him.

* A foreign substance that resembles a natural body substance may enter the body. Immune system with less caution can make similar body compounds such foreign material as the target. For example, the bacteria that cause sore throat has several antigens that are similar to human heart cells. Rarely occurs, the immune system can attack the heart after sore throat (this part of the fever reaction rumatik).

* The cells that control antibody production, for example, B lymphocytes (one of the white blood cells) may be damaged and result in abnormal antibodies that attack some body cells.

autoimmune disorders symptoms

Offspring may be involved in some autoimmune disorders. Vulnerability chaos, rather than the disorder itself, may be inherited. In susceptible people, a trigger, such as a viral infection or tissue damage, can create chaos develops. Hormonal factors may also be involved, because many autoimmune disorders are more common in women. Autoimmune Disorders

SYMPTOMS

Autoimmune disorders can cause fever. However, symptoms vary depending on the disorder and the affected body part. Some autoimmune disorders affect certain types of tissues throughout the body, for example, blood vessels, cartilage, or skin. Other autoimmune disorders affect specific organs. Actually any organ, including kidneys, lungs, heart, and brain, can be affected. Result of inflammation and tissue damage can cause pain, deformed joints, weakness, jaundice, itching, difficulty breathing, fluid retention (edema), fever, and even death.

Diagnosis

Blood tests that indicate the presence of inflammation can be suspected as an autoimmune disorder. For example, the erythrocyte sedimentation rate (ESR) is often increased, because the protein produced in response to inflammation impairs the ability of red blood cells (erythrocytes) to remain in the blood. Often, the number of red blood cells (anemia) due to inflammation reducing their production. However, inflammation has many causes, many of which are not autoimmune. That way, doctors often get a blood test to detect different antibodies that can occur in people who have a specific autoimmune disorders. Examples of these antibodies are antinuclear antibodies, which usually exist in systemic lupus erythematosus, and rheumatoid factor or anti-cyclic citrullinated peptide (anti-CCP) antibodies, which usually exist in rheumatoid arthritis. But even this antibody may occasionally occur in people who do not have an autoimmune disorder, so doctors usually use a combination of test results and signs and symptoms of people to make a decision whether there is an autoimmune disorder.

autoimmune disorders list